The first woman to win a Nobel Prize was Marie Curie, who won the Nobel Prize in Physics in 1903 with her husband, Pierre Curie, and Henri Becquerel. Curie is also the first person and the only woman to have won multiple Nobel Prizes; in 1911, she won the Nobel Prize in Chemistry. Curie's daughter, Irène Joliot-Curie, won the Nobel Prize in Chemistry in 1935, making the two the only mother-daughter pair to have won Nobel Prizes.

Source: Wikipedia